Product Description of Diethyl Sebacate (CAS No. 110-40-7)
Diethyl sebacate is a clear, colorless to pale yellow liquid characterized by a mild wine-like, fruity, and melon-inspired aroma. With its high boiling point of approximately 302°C and low melting range of 1–3°C, it demonstrates good thermal stability and handling flexibility.
This ester compound is insoluble in water while showing excellent miscibility with ethanol, ether, non-volatile oils, and various organic solvents. Due to its favorable solvency, pleasant odor profile, and stable chemical properties, diethyl sebacate is widely used in fragrance, flavor, chemical synthesis, and specialty formulation applications.
Diethyl sebacate Chemical Properties
| Melting point | 1-2 °C (lit.) |
| Boiling point | 312 °C (lit.) |
| Density | 0.963 g/mL at 25 °C (lit.) |
| Vapor pressure | 0.018Pa at 25℃ |
| Refractive index | n20/D 1.436(lit.) |
| FEMA | 2376 | DIETHYL SEBACATE |
| Fp | >230 °F |
| Storage temp. | Store below +30°C. |
| Solubility | <0.1g/l |
| Form | liquid |
| Color | colorless to pale yellow |
| Odor | mild melon fruity quince wine |
| Odor Type | fruity |
| Water Solubility | slightly soluble |
| JECFA Number | 624 |
| Merck | 148,415 |
| BRN | 1790779 |
| Dielectric constant | 5.0（30℃） |
| LogP | 4.64 at 20℃ |
| CAS DataBase Reference | 110-40-7(CAS DataBase Reference) |
| NIST Chemistry Reference | Decanedioic acid, diethyl ester(110-40-7) |
| EPA Substance Registry System | Decanedioic acid, diethyl ester (110-40-7) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 38 |
| Safety Statements | 36-24/25 |
| WGK Germany | 2 |
| RTECS | VS1180000 |
| HS Code | 29171390 |
| Toxicity | LD50 orally in Rabbit: 14470 mg/kg |
Product Application of Diethyl Sebacate (CAS No. 110-40-7)
Diethyl sebacate is a versatile ester compound with applications across the flavor, fragrance, and pharmaceutical industries. Approved for use as a temporary food flavoring ingredient according to GB 2760-96, it is mainly utilized in the preparation of berry-style flavor compositions and as a solvent or carrier for various fruit flavor formulations.
In addition to its role in flavor and fragrance applications, diethyl sebacate can also serve as a functional ingredient in pharmaceutical-related processes, benefiting from its excellent solvent properties, chemical stability, and compatibility with organic compounds.
