Product Description of Dioctyl Sulfosuccinate Sodium Salt (CAS No. 577-11-7)
Dioctyl sulfosuccinate sodium salt, also known as docusate sodium, is a widely used pharmaceutical excipient and stool-softening agent. It facilitates easier bowel movements by promoting water penetration into stools, making it a commonly selected ingredient in constipation relief formulations.
Beyond its traditional medical applications, docusate sodium has demonstrated versatility in pharmaceutical technology, including its use in advanced drug-delivery systems. It can be incorporated into electrospun fiber platforms and other formulation approaches designed for controlled and targeted release of active pharmaceutical ingredients, supporting improved therapeutic performance.
Dioctyl sulfosuccinate sodium salt Chemical Properties
| Melting point | 173-179 °C(lit.) |
| Boiling point | 82.7°C |
| Density | 1.1 |
| Vapor pressure | 0Pa at 25℃ |
| Storage temp. | Inert atmosphere,Room Temperature |
| Solubility | methanol: 0.1 M at 20 °C, clear, colorless |
| Form | Waxy Solid |
| Color | White |
| Specific Gravity | 1.005_PERCENT VOLATILE: 40 |
| Water Solubility | 1.5 g/100 mL (25 ºC) |
| Sensitive | Hygroscopic |
| λmax | λ: 260 nm Amax: 0.1 |
| λ: 280 nm Amax: 0.05 | |
| Merck | 143,401 |
| BRN | 4117588 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| InChIKey | APSBXTVYXVQYAB-UHFFFAOYSA-M |
| LogP | 1.998 at 20℃ |
| CAS DataBase Reference | 577-11-7(CAS DataBase Reference) |
| EPA Substance Registry System | Bis(2-ethylhexyl) sodium sulfosuccinate (577-11-7) |
Safety Information
| Hazard Codes | Xn,Xi |
| Risk Statements | 22-38-41-36/37/38 |
| Safety Statements | 26-39-37/39-36 |
| WGK Germany | 2 |
| RTECS | WN0525000 |
| F | 3-10 |
| TSCA | Yes |
| HS Code | 29171900 |
| Hazardous Substances Data | 577-11-7(Hazardous Substances Data) |
| Toxicity | LD50 oral in rat: 1900mg/kg |
Product Application of Dioctyl Sulfosuccinate Sodium Salt (CAS No. 577-11-7)
Dioctyl sulfosuccinate sodium salt (Docusate sodium, also known as Aerosol OT) is a multifunctional surfactant widely used in pharmaceutical, textile, cosmetic, and chemical industries due to its excellent emulsifying, wetting, and dispersing properties.
In the pharmaceutical field, it is commonly utilized as a stool-softening agent for constipation relief and serves as a functional component in advanced drug-delivery systems, including electrospun fiber materials designed for controlled release of active ingredients.
In textile processing, dioctyl sulfosuccinate sodium salt acts as an effective emulsifier, penetrant, detergent, wetting agent, and leveling additive, improving surface wettability, penetration efficiency, and formulation stability. It is also applied in printing and dyeing processes, as well as in cosmetic formulations requiring superior surfactant performance.
Furthermore, Aerosol OT is used in specialized chemical applications, including microemulsion systems, analytical electrophoresis technologies, reversed-phase microparticle preparation, and protein solubilization processes. Its strong interfacial activity and compatibility with various formulations make it a valuable surfactant for diverse industrial applications.
