Pagoclone CAS#133737-32-3

Selective GABA Receptor Modulating Activity:
Pagoclone is a novel cyclopyrrolone compound that selectively interacts with GABA (gamma-aminobutyric acid) receptors, modulating inhibitory neurotransmission through targeted effects on the GABAergic system.

Potential Neurological Application Value:
Pagoclone has been investigated for its potential role in reducing stuttering symptoms by influencing the activity of GABA(A) receptors, providing insights into new approaches for neurological condition research.

Unique Cyclopyrrolone Chemical Structure:
As a distinctive cyclopyrrolone derivative, Pagoclone exhibits a unique pharmacological profile compared with traditional GABA-related compounds, offering valuable research potential in neuropharmacology.

Partial GABA(A) Receptor Agonist Properties:
Pagoclone functions as a partial agonist of GABA(A) receptors, enabling selective regulation of inhibitory signaling pathways and supporting research into GABA-mediated neurological mechanisms.

Product Description of Pagoclone CAS#133737-32-3

Pagoclone is a selective GABA receptor modulator belonging to the cyclopyrrolone class of compounds. It has been studied for its interaction with the GABA(A) receptor system and its potential effects on regulating neuronal activity.

By acting as a partial agonist at GABA(A) receptors, Pagoclone demonstrates a distinct mechanism of action compared with other GABAergic agents. Its unique molecular structure and receptor selectivity make it a compound of interest in neuroscience research, pharmacological studies, and the investigation of GABA-related pathways.

Pagoclone CAS#133737-32-3

PAGOCLONE Chemical Properties

Boiling point 582.1±50.0 °C(Predicted)
density 1.273±0.06 g/cm3(Predicted)
pka1.62±0.30(Predicted)
InChIInChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3
InChIKeyHIUPRQPBWVEQJJ-UHFFFAOYSA-N
SMILESC1(=O)C2=C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1=CC=C2C(=N1)N=C(Cl)C=C2

Product Application of Pagoclone CAS#133737-32-3

Pagoclone is a selective modulator of GABA (gamma-aminobutyric acid) receptors that has been studied for its potential application in neurological research, particularly in the investigation of stuttering symptom management.

As a novel cyclopyrrolone derivative, Pagoclone exhibits unique pharmacological properties by acting as a partial agonist of the GABA(A) receptor, enabling targeted regulation of GABAergic neurotransmission. Its selective receptor activity makes it a valuable compound for research related to central nervous system function, neuropharmacology, and GABA-mediated signaling pathways.

Pagoclone CAS#133737-32-3

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