Product Description of Pagoclone CAS#133737-32-3
Pagoclone is a selective GABA receptor modulator belonging to the cyclopyrrolone class of compounds. It has been studied for its interaction with the GABA(A) receptor system and its potential effects on regulating neuronal activity.
By acting as a partial agonist at GABA(A) receptors, Pagoclone demonstrates a distinct mechanism of action compared with other GABAergic agents. Its unique molecular structure and receptor selectivity make it a compound of interest in neuroscience research, pharmacological studies, and the investigation of GABA-related pathways.

PAGOCLONE Chemical Properties
| Boiling point | 582.1±50.0 °C(Predicted) |
| density | 1.273±0.06 g/cm3(Predicted) |
| pka | 1.62±0.30(Predicted) |
| InChI | InChI=1S/C23H22ClN3O2/c1-14(2)7-10-16(28)13-19-17-5-3-4-6-18(17)23(29)27(19)21-12-9-15-8-11-20(24)25-22(15)26-21/h3-6,8-9,11-12,14,19H,7,10,13H2,1-2H3 |
| InChIKey | HIUPRQPBWVEQJJ-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=CC=C2)C(CC(=O)CCC(C)C)N1C1=CC=C2C(=N1)N=C(Cl)C=C2 |
Product Application of Pagoclone CAS#133737-32-3
Pagoclone is a selective modulator of GABA (gamma-aminobutyric acid) receptors that has been studied for its potential application in neurological research, particularly in the investigation of stuttering symptom management.
As a novel cyclopyrrolone derivative, Pagoclone exhibits unique pharmacological properties by acting as a partial agonist of the GABA(A) receptor, enabling targeted regulation of GABAergic neurotransmission. Its selective receptor activity makes it a valuable compound for research related to central nervous system function, neuropharmacology, and GABA-mediated signaling pathways.

