Product Description of DMI CAS#80-73-9
1,3-Dimethyl-2-imidazolidinone (DMI), also known as dimethylethylene urea, is a high-boiling polar organic solvent widely recognized for its excellent solvency, stability, and safety profile.
DMI exhibits outstanding dissolving capability for various chemical substances and is widely used as a solvent in organic synthesis, pharmaceutical manufacturing, electronic materials, coatings, and specialty chemical applications. Its high flash point, low melting point, and low toxicity provide significant advantages in industrial processing.
The compound demonstrates excellent resistance to strong acids, strong bases, moisture, light, and oxygen, maintaining stable chemical properties during storage and application. With its combination of high solvency, thermal stability, and environmental advantages, DMI is an important solvent choice for advanced chemical and industrial processes.

1,3-Dimethyl-2-imidazolidinone Chemical Properties
| Melting point | 8.2 °C |
| Boiling point | 224-226 °C (lit.) |
| density | 1.056 g/mL at 25 °C (lit.) |
| vapor pressure | <1 hPa (20 °C) |
| refractive index | n20/D 1.472(lit.) |
| Fp | 220 °F |
| storage temp. | Store at +5°C to +30°C. |
| solubility | toluene: soluble(lit.) |
| pka | -0.65±0.20(Predicted) |
| form | Liquid |
| color | Clear |
| explosive limit | 1.3-8.4%(V) |
| Water Solubility | freely soluble |
| Sensitive | Hygroscopic |
| Merck | 143,249 |
| BRN | 108808 |
| InChIKey | CYSGHNMQYZDMIA-UHFFFAOYSA-N |
| LogP | -0.3 at 25℃ |
| CAS DataBase Reference | 80-73-9(CAS DataBase Reference) |
| NIST Chemistry Reference | 1,3-Dimethyl-2-imidazolidinone(80-73-9) |
| EPA Substance Registry System | N,N'-Dimethylimidazolidinone (80-73-9) |
Safety Information
| Hazard Codes | Xn,Xi |
| Risk Statements | 21/22-38-41-36/38-62-22 |
| Safety Statements | 26-36-36/37/39-36/37 |
| RIDADR | UN 2810 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | NJ0660000 |
| F | 3 |
| Autoignition Temperature | 305 °C |
| Hazard Note | Harmful/Irritant |
| TSCA | Yes |
| HazardClass | 6.1 |
| PackingGroup | Ⅲ |
| HS Code | 29332990 |
| Toxicity | LD50 orally in Rabbit: 1261 mg/kg LD50 dermal Rabbit 986 mg/kg |
Product Application of DMI CAS#80-73-9
1,3-Dimethyl-2-imidazolidinone (DMI) is a versatile high-polarity organic solvent widely used in organic synthesis and advanced chemical processes. Due to its excellent solvency and chemical stability, it is suitable for dissolving a variety of organic compounds and supporting numerous synthetic reactions.
In chemical research, DMI is commonly employed as an inert dipolar solvent and is used in photochemical studies involving the formation of stable functionalized hydrogenated silane biradical transition-metal complexes from arylsilane compounds. Its favorable safety profile makes it a preferred alternative to traditional high-polarity solvents such as hexamethylphosphoramide (HMPA).
As an important ketone-based organic compound and chemical intermediate, DMI is widely applied in multiple industries, including pharmaceuticals, agrochemicals, dyes, liquid crystal materials, electronic chemicals, and specialty chemical manufacturing.
With its strong dissolving ability, high thermal stability, and low environmental impact, DMI serves as an efficient solvent choice for modern chemical synthesis and industrial applications.

