Product Description
Diethyl carbonate (DEC) (CAS No. 105-58-8) is a versatile organic compound featuring unique chemical structures that provide excellent reactivity and solvent performance. It is widely recognized as an important reagent and functional solvent in organic synthesis and industrial manufacturing.
Due to its active carbonyl-related groups, diethyl carbonate is commonly involved in chemical transformations such as carbonylation, alkylation, and carbethoxylation reactions, serving as a valuable building block for the preparation of various organic compounds.
DEC is a clear, colorless liquid with excellent solvent properties. As an aprotic and relatively environmentally friendly solvent, it is widely used in chemical processing, coating formulations, polymer applications, and specialty chemical systems. It also shows good compatibility with nitrocellulose, cellulose ethers, and different resin materials.
With its combination of high reactivity, excellent solvency, and broad application flexibility, diethyl carbonate is an important chemical material for organic synthesis, industrial formulations, and advanced material processing.
Melting point | -43 °C (lit.) |
Boiling point | 126-128 °C (lit.) |
density | 0.975 g/mL at 25 °C (lit.) |
vapor density | 4.1 (vs air) |
vapor pressure | 10 mm Hg ( 23.8 °C) |
refractive index | n20/D 1.384(lit.) |
Fp | 88 °F |
storage temp. | no restrictions. |
solubility | 18.8mg/l insoluble |
form | Liquid |
color | Clear |
Odor | Pleasant, etheral; mild and nonresidual. |
PH | 6.3 (1g/l, H2O) |
explosive limit | 1.4-11.0%(V) |
biological source | mouse |
Water Solubility | Negligible |
Sensitive | Moisture Sensitive |
Merck | 143780 |
BRN | 956591 |
Henry's Law Constant | 1.0×10-1 mol/(m3Pa) at 25℃, Burkholder et al. (2019) |
Dielectric constant | 2.8（Ambient） |
Stability: | Stable. Flammable. Incompatible with strong acids, strong bases, reducing agents, oxidizing agents. Protect from moisture. |
InChI | 1S/C5H10O3/c1-3-7-5(6)8-4-2/h3-4H2,1-2H3 |
InChIKey | OIFBSDVPJOWBCH-UHFFFAOYSA-N |
SMILES | O=C(OCC)OCC |
LogP | 1.21 at 25℃ |
Surface tension | 29.2 mN/m at 273.18K |
CAS DataBase Reference | 105-58-8(CAS DataBase Reference) |
NIST Chemistry Reference | Carbonic acid, diethyl ester(105-58-8) |
EPA Substance Registry System | Diethyl carbonate (105-58-8) |
Safety Information
Hazard Codes | T,Xi |
Risk Statements | 23/24/25-36/37/38-10 |
Safety Statements | 26-36-45-16-23 |
RIDADR | UN 2366 |
WGK Germany | 3 |
RTECS | YE1050000 |
F | 21 |
Autoignition Temperature | 445 °C |
TSCA | TSCA listed |
HS Code | 2920 90 10 |
HazardClass | 3 |
PackingGroup | III |
Storage Class | 3 - Flammable liquids |
Hazard Classifications | Flam. Liq. 3 |
Hazardous Substances Data | 105-58-8(Hazardous Substances Data) |
Toxicity | LD50 orally in Rabbit: > 4900 mg/kg |
LC50 (inhalation) > 21 mg/kg (mouse) | |
TDL0 500 mg/kg (mouse) | |
LD50 (s.c.) 8500 mg/kg (rat) |
Applications of Diethyl Carbonate CAS No. 105-58-8
Diethyl carbonate (DEC) is a versatile organic compound widely used in chemical synthesis, pharmaceutical manufacturing, and industrial formulation processes due to its excellent reactivity and solvent properties.
Organic and Pharmaceutical Synthesis
Diethyl carbonate serves as an important intermediate and reaction reagent in organic synthesis. It is widely utilized in the preparation of fine chemicals, pharmaceutical intermediates, and specialty compounds through various chemical transformation processes.
Industrial Solvent Applications
With excellent solvency and compatibility, DEC is commonly used as a solvent for resins, oils, nitrocellulose, cellulose ethers, and other organic materials. It helps improve formulation stability and processing performance in coatings, polymers, and chemical products.
Coatings and Specialty Chemical Applications
Diethyl carbonate is also applied in coating systems and specialty chemical formulations where a high-performance, environmentally preferable solvent is required.
Due to its strong chemical versatility, good material compatibility, and favorable solvent characteristics, diethyl carbonate plays an important role in organic synthesis,
