Product Description of Guanidine Hydrochloride 99.5% CAS#50-01-1
Guanidine Hydrochloride, also known as carbamidine hydrochloride, is an inorganic salt compound that appears as a white to slightly yellow crystalline solid. It is characterized by low solubility in organic solvents such as acetone, benzene, and ether.
Due to its active guanidine functional group, Guanidine Hydrochloride exhibits excellent chemical versatility and is widely used as a key intermediate in the manufacture of pharmaceutical ingredients, pesticides, dyes, and other organic compounds.
In the pharmaceutical industry, it serves as an important precursor for the synthesis of several medicinal products, including sulfonamide drugs and folic acid derivatives. In addition, its antistatic properties allow it to be applied in synthetic fiber treatment, making it a multifunctional material for chemical, pharmaceutical, and industrial applications.
Product Parameters of Guanidinehydrochloride99.5%CAS#50-01-1
| CAS | No. 50-01-1 |
| CID | 5742 |
| EINECS(EC#) | 200-002-3 |
| Molecular Formula | CH6ClN3 (isomer) |
| Inchi | InChI=1S/CH5N3.ClH/c2-1(3)4;/h(H5,2,3,4);1H |
| InChIkey | PJJJBBJSCAKJQF-UHFFFAOYSA-N |
| Canonical Smiles | C(=N)(N)N.Cl |
| Isomers Smiles | C(=N)(N)N.Cl |
| Density | 1.18 g/mL at 25 °C(lit.) |
| Melting point | 180-185 °C(lit.) |
| Boiling point | 132.9 °C at 760 mmHg |
| Refractive index | n20/D 1.465 |
| Flash Point | 34.2 °C |
| Precise Quality | 95.025 |
| PSA | 75.89 |
| logP | 1.1409 |
| Solubility | H2O: 6?M, clear, colorless |
| Appearance | DryPowder; DryPowder, Liquid |
| Storage | Store at RT. |
| Chemical Properties | White cryst. powder |
| Color/Form | White to slightly yellow |
| Odo | Odorless |
| PH | 4.5-5.5 (100g/l, H2O, 20℃) |
| Water Solubility | H2O: 2280 g/L (20 oC) |
| Stability | Stable. Hygroscopic. Incompatible with strong oxidizing agents. |
| StorageTemp | Store at RT. |
Product Application of Guanidine Hydrochloride 99.5% CAS#50-01-1
Guanidine Hydrochloride is a versatile chemical intermediate widely applied in the synthesis of pharmaceuticals, pesticides, dyes, and other specialty chemicals. Its active guanidine structure enables it to participate in various organic reactions, making it an important raw material in fine chemical manufacturing.
It is commonly used for the preparation of aminopyrimidine derivatives, including 2-aminopyrimidine, 2-amino-6-methylpyrimidine, and 2-amino-4,6-dimethylpyrimidine. These compounds serve as valuable intermediates in the production of pharmaceutical ingredients, especially sulfonamide drugs such as sulfadiazine, sulfamethylpyrimidine, and sulfamethazine.
In addition, Guanidine Hydrochloride (or guanidine nitrate) can react with ethyl cyanoacetate to produce 2,4-diamino-6-hydroxypyrimidine, an important intermediate used in the synthesis of folic acid and related pharmaceutical compounds.
Beyond pharmaceutical applications, Guanidine Hydrochloride also finds use as a functional additive for synthetic fibers, where it can act as an antistatic agent to improve fiber performance and processing characteristics. Its broad application range makes it a valuable intermediate across pharmaceutical, chemical, and material industries.
