Product Description
5-Methoxy-2-tetralone (CAS No. 32940-15-1) is an aromatic tetralone derivative commonly used as an intermediate in pharmaceutical and fine chemical synthesis. It features a methoxy-substituted cyclic ketone structure, offering valuable reactivity for the preparation of structurally diverse compounds.
The compound has the molecular formula C₁₁H₁₂O₂ and is typically present as a yellow to orange solid. Its well-defined chemical structure and stable properties make it suitable for use in research and development applications involving complex organic molecules.
Due to its versatile reactivity and role as a synthetic building block, 5-methoxy-2-tetralone is widely applied in pharmaceutical chemistry, medicinal research, and the development of specialty organic compounds.
5-Methoxy-2-tetralone Chemical Properties
| Melting point | 32-36 °C (lit.) |
| Boiling point | 165°C/10mmHg(lit.) |
| density | 1.124±0.06 g/cm3(Predicted) |
| vapor pressure | 0.059Pa at 25℃ |
| Fp | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Chloroform, Dichloromethane, Ethyl Acetate, Methanol |
| form | Solid |
| color | Yellowish Orange |
| BRN | 1451623 |
| InChIKey | MDAIAXRTLTVEOU-UHFFFAOYSA-N |
| LogP | 1.8 at 25℃ |
| CAS DataBase Reference | 32940-15-1(CAS DataBase Reference) |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-36-24/25 |
| WGK Germany | 3 |
| HS Code | 29145090 |
Applications of 5-Methoxy-2-Tetralone CAS No. 32940-15-1
5-Methoxy-2-tetralone is an important synthetic intermediate widely used in pharmaceutical research and advanced organic chemistry due to its versatile molecular structure and excellent reactivity.
Pharmaceutical Intermediate Applications
5-Methoxy-2-tetralone serves as a valuable building block in the synthesis of various biologically active compounds. It is particularly utilized in the preparation of rotigotine, a dopamine receptor agonist commonly studied for applications related to Parkinson’s disease and restless legs syndrome.
Organic Synthesis and Research Applications
In laboratory and chemical research, 5-methoxy-2-tetralone is frequently used as a starting material for constructing complex molecular frameworks, including polycyclic aromatic compounds and functionalized naphthalene derivatives.
Advanced Chemical Development
Due to its adaptable tetralone structure, the compound supports a wide range of synthetic transformations, making it a useful intermediate in medicinal chemistry, fine chemical development, and the exploration of novel bioactive molecules.
With its broad synthetic versatility and important role in pharmaceutical chemistry, 5-methoxy-2-tetralone remains a valuable raw material for research and specialty chemical applications.
