Product Description
Isopropyl palmitate (CAS No. 142-91-6) is a widely used cosmetic ester and emollient valued for its excellent spreading properties, smooth texture, and skin-conditioning performance.
With its lightweight feel and rapid absorption characteristics, isopropyl palmitate is commonly incorporated into skincare and personal care formulations as a carrier, emollient, or texture-enhancing ingredient. It helps improve the application feel of creams, lotions, and other cosmetic products while providing a soft and silky skin finish.
The ingredient demonstrates good chemical stability and resistance to oxidation, helping preserve formulation consistency and prevent unwanted odor development during storage. Its ability to provide nourishment without a heavy or greasy sensation makes it especially suitable for modern cosmetic products focused on comfort and elegance.
Due to its excellent sensory properties, formulation compatibility, and stable performance, isopropyl palmitate is an important ingredient widely used in skincare, cosmetics, and personal care applications.

Isopropyl palmitate Chemical Properties
| Melting point | 11-13 °C (lit.) |
| Boiling point | 160°C 2mm |
| Density | 0.852 g/mL at 25 °C (lit.) |
| Vapor pressure | 0.007Pa at 25℃ |
| Refractive index | n20/D 1.438(lit.) |
| Fp | >230 °F |
| Storage temp | 2-8°C |
| Solubility | <0.001g/l |
| Color | Colourless |
| Odor | very sl. odor |
| Water Solubility | Not miscible or difficult to mix with water. |
| BRN | 1786567 |
| InChIKey | XUGNVMKQXJXZCD-UHFFFAOYSA-N |
| LogP | 8.16 |
| CAS DataBase Reference | 142-91-6(CAS DataBase Reference) |
| NIST Chemistry Reference | Isopropyl palmitate(142-91-6) |
| EPA Substance Registry System | Isopropyl palmitate (142-91-6) |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 36/38-36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | - |
| RTECS | RT4900000 |
| TSCA | Yes |
| HS Code | 29157090 |
| Hazardous Substances Data | 142-91-6(Hazardous Substances Data) |
| Toxicity | mouse,LD50,intraperitoneal,100mg/kg (100mg/kg),National Technical Information Service. Vol. AD277-689, |
Applications of Isopropyl Palmitate CAS No. 142-91-6
Isopropyl palmitate is a versatile cosmetic ester widely used in personal care formulations due to its excellent emollient properties, skin compatibility, and ability to improve product texture and performance.
Skincare Applications
Isopropyl palmitate is commonly used as a skin-conditioning agent and moisturizer in cosmetic formulations. It provides a smooth, soft feel while helping improve the spreadability and absorption of skincare products, leaving the skin comfortable and silky without a heavy greasy sensation.
Penetration Enhancement Applications
As an effective cosmetic penetration enhancer, isopropyl palmitate can help improve the delivery efficiency of active ingredients in formulations by enhancing their interaction with the skin, supporting better product performance.
Hair Care and Personal Care Applications
Due to its excellent conditioning properties and lightweight texture, isopropyl palmitate is widely used in hair conditioners and personal care products to improve softness, smoothness, and overall sensory experience.
Common Product Applications
Isopropyl palmitate is frequently incorporated into a variety of cosmetic products, including sunscreens, sun care products, bath oils, facial and body creams, lotions, shaving products, and other personal care formulations.
Typically, isopropyl palmitate is added to cosmetic formulations at recommended levels of approximately 2–10%, depending on the product type and desired performance.
With its excellent moisturizing effect, skin-friendly characteristics, and multifunctional performance, isopropyl palmitate remains an important ingredient in modern skincare and personal care formulations.

