Product Description
(1S,2S)-(+)-Pseudoephedrine hydrochloride (CAS No. 345-78-8) is a high-purity pharmaceutical intermediate that appears as a white crystalline powder. It has excellent water solubility, slight solubility in ethanol, and is insoluble in solvents such as trichloromethane and ether.
With its stable chemical properties and chiral structure, (1S,2S)-(+)-Pseudoephedrine hydrochloride plays an important role in pharmaceutical synthesis and organic chemistry. It is commonly used as a key ingredient in the manufacture of compound cold medicines and serves as an intermediate for preparing a variety of organic compounds.
Due to its reliable quality, favorable solubility characteristics, and broad synthetic utility, (1S,2S)-(+)-Pseudoephedrine hydrochloride is widely applied in pharmaceutical manufacturing, fine chemical synthesis, and related research fields.

(1S,2S)-(+)-Pseudoephedrine hydrochloride Chemical Properties
| Product Name: | (1S,2S)-(+)-Pseudoephedrine hydrochloride |
| Synonyms: | (+)-PSI-EPHEDRINE HYDROCHLORIDE;PSI-EPHEDRINE HYDROCHLORIDE;PSEUDOEPHEDRINE HCL;PSEUDOEPHEDRINE HCL, (+)-1S,2S-;PSEUDOEPHEDRINE HYDROCHLORIDE;a)]-;alpha-(1-(methylamino)ethyl)-,hydrochloride,(s-(r*,r*))-benzenemethano;benzenemethanol,alpha-[1-(methylamino)ethyl]-,hydrochloride,[s-(theta,thet |
| CAS: | 345-78-8 |
| MF: | C10H16ClNO |
| MW: | 201.69 |
| EINECS: | 206-462-1 |
| Product Categories: | Pharmaceutical Raw Materials;Amines;Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Pharmaceuticals;API's |
| Mol File: | 345-78-8.mol |
| Melting point | 185-188 °C(lit.) |
| alpha | 61 º (c=5, H2O,2dm tube) |
| storage temp. | Refrigerator (+4°C) |
| solubility | Freely soluble in water and in ethanol (96 per cent), sparingly soluble in methylene chloride. |
| pka | 9.22(at 25℃) |
| form | buffered aqueous solution |
| biological source | rabbit |
| Merck | 138007 |
| BRN | 3915112 |
| LogP | -1.74 at 23℃ and pH7 |
| CAS DataBase Reference | 345-78-8(CAS DataBase Reference) |
| EPA Substance Registry System | Benzenemethanol, .alpha.-[(1S)-1-(methylamino)ethyl]-, hydrochloride, (.alpha.S)- (345-78-8) |
Product Usage of (1S,2S)-(+)-Pseudoephedrine Hydrochloride CAS No. 345-78-8
(1S,2S)-(+)-Pseudoephedrine hydrochloride is an important chiral intermediate widely used in organic synthesis and pharmaceutical-related applications. Its unique molecular structure and reactive functional groups enable it to participate in various chemical transformations, making it a valuable building block for the preparation of complex organic compounds.
Organic Synthesis Applications
As a versatile synthesis intermediate, (1S,2S)-(+)-Pseudoephedrine hydrochloride is utilized in the development and production of structurally specific organic molecules. It provides an effective starting material for the synthesis of fine chemicals and specialty compounds.
Pharmaceutical Intermediate Applications
Due to its chiral characteristics and reliable chemical performance, it plays an important role in pharmaceutical research and manufacturing processes, serving as an intermediate for the preparation of various pharmaceutical-related compounds.
Fine Chemical Industry Uses
With excellent synthetic versatility, (1S,2S)-(+)-Pseudoephedrine hydrochloride supports the production of high-value fine chemicals and contributes to the development of advanced chemical products.
Its stable properties, functional adaptability, and role as a chiral building block make (1S,2S)-(+)-Pseudoephedrine hydrochloride an important material in organic chemistry, pharmaceutical synthesis, and fine chemical industries.

