Product Description
Benzyldimethylhexadecylammonium chloride (CAS No. 122-18-9), also known as hexadecyl dimethyl benzyl ammonium chloride or cetaxonium chloride, is a cationic quaternary ammonium surfactant belonging to the benzalkonium chloride family.
It is characterized by a long-chain alkyl structure, strong lipophilic properties, and functional surface activity. As one of the components related to benzalkonium chloride compounds, it demonstrates excellent antimicrobial performance and is commonly used in applications requiring preservation and microbial inhibition.
Due to its surfactant properties and biological compatibility, benzyldimethylhexadecylammonium chloride is used as an antimicrobial agent, preservative, and pharmaceutical excipient. It is applied in pharmaceutical research and formulation development involving oral, throat, and ophthalmic preparations, where it contributes to product stability and microbial protection.
With its versatile chemical properties, this compound serves as a valuable functional material in pharmaceutical, chemical, and specialty formulation industries.

Benzyldimethylhexadecylammonium chloride Chemical Properties
| Melting point | 55-65 °C(lit.) |
| Boiling point | 550.14°C (rough estimate) |
| Density | 0.9089 (rough estimate) |
| Vapor pressure | 0Pa at 25℃ |
| Refractive index | 1.6000 (estimate) |
| Storage temp. | room temp |
| Solubility | DMSO: 100 mg/mL (252.47 mM) |
| Form | Powder |
| Color | White to creamy-white |
| Water Solubility | MODERATELY SOLUBLE |
| Merck | 142,017 |
| BRN | 3802341 |
| LogP | 3.022 at 25℃ |
| CAS DataBase Reference | 122-18-9(CAS DataBase Reference) |
| EPA Substance Registry System | Benzyl hexadecyl dimethyl ammonium chloride (122-18-9) |
Safety Information
| Hazard Codes | Xi,N,C |
| Risk Statements | 36/37/38-50/53-50-34-21/22 |
| Safety Statements | 61-45-36/37/39-26-60 |
| RIDADR | UN 3077 9/PG 3 |
| WGK Germany | 3 |
| RTECS | BO6822450 |
| F | 3 |
| TSCA | Yes |
| HazardClass | 8 |
| HS Code | 29239000 |
| Toxicity | eye-rbt 150 mg MLD ARZNAD 9,349,59 |
| Hazard Codes | Xi,N,C |
| Risk Statements | 36/37/38-50/53-50-34-21/22 |
| Safety Statements | 61-45-36/37/39-26-60 |
| RIDADR | UN 3077 9/PG 3 |
Product Application of Benzyldimethylhexadecylammonium Chloride CAS No. 122-18-9
Benzyldimethylhexadecylammonium chloride is widely used as a functional ingredient in pharmaceutical and chemical applications. It serves as an important pharmaceutical raw material and is also utilized as a cationic surfactant, catalyst, emulsifying agent, disinfectant, and antimicrobial component.
In industrial and formulation processes, it can be applied as a bactericidal agent, antistatic additive, and surface-active ingredient, providing excellent performance in microbial control, emulsion stabilization, and specialty chemical formulations. Its versatile properties make it valuable across pharmaceutical, chemical, and related industries.

